U.S. Department of Health and Human Services Helping our clients shape the future 2026-HC-WEB-015 HHS Partner Page desktop large 1440x600 2026-HC-WEB-015 HHS Partner Page mobile 428x332 2026-HC-WEB-015 HHS Partner Page tablet 1024x920 Overview Services Agencies Agencies we serve Insights Connect We support the U.S. Department of Health and Human Services (HHS) and its Office of the Secretary (OS) in protecting and promoting the health and well-being of Americans. This includes strengthening program integrity, developing durable, sustainable strategies, supporting workforce development, and enhancing the quality and impact of public health programs through data-informed action. Connect with an expert Data We develop and apply robust data governance and interoperability frameworks to improve data quality, security, and compliance with regulatory standards. We partner with leaders to foster a culture of data literacy, empowering teams to effectively interpret and utilize data in decision-making. We’ve helped our clients: ​ Develop data pipelines and analytics infrastructure Design and execute quantitative and qualitative data analysis projects Create data standards and definitions aligned with federal requirements Support data policy development and implementation Data transformation and analytics Data & Analytics Grant Management We use artificial intelligence (AI) and machine learning (ML) technologies to transform grant lifecycle management. Our solutions forecast funding trends, accelerate review processes, and facilitate compliance with federal mandates. We’ve helped our clients: ​ Design and deploy AI-powered grant application review tools that assess applications against NOFO criteria with precision and transparency Develop automated quality assurance systems for grant compliance and terminology reviews Create intelligent screening tools that flag non-compliant applications and recommend remediation actions Build client-facing dashboards for real-time grant processing status and analytics AI-powered grants management solutions Grants Management Mission Services We deliver end-to-end mission support solutions that strengthen operational efficiency, bolster program integrity, and enable agencies to achieve strategic objectives. Our approach integrates process optimization, workforce enablement, and technology-driven tools to ensure programs run smoothly and effectively. We’ve helped our clients: ​ Design performance measurement frameworks that track progress against agency goals Strengthen program integrity through improved oversight, controls, and risk mitigation Create centralized knowledge management systems for streamlined collaboration and decision-making Implement succession planning and talent readiness programs Identify and address workforce skill gaps through training and technical assistance Transforming goals into action Mission Strategy & Execution Business Ops and Tech We provide comprehensive business and operations support, applying our deep expertise in financial management and transformation across public and private sectors. Powered by technology that solves real business needs—including automation, workflow tools, and analytics—our solutions strengthen governance, streamline business processes, and drive efficiency and effectiveness. We’ve helped our clients: ​ Optimize budget, financial planning, and audit workflows Conduct compliance reviews and re-engineering of financial processes Support acquisition policy development and HHSAR management Create centralized system hubs and digital tools that provide streamlined access to resources Tech-enabled financial and business support Business Operations & Technology Our services ACF We are helping multiple offices within ACF improve child health and wellbeing through: Technical assistance for states AI-powered grant management and business intelligence dashboards Data governance and policy operations support Administration for Children and Families (ACF) HRSA We are helping HRSA modernize operational services that support effective oversight of the Organ Procurement and Transplantation Network (OPTN). Our support includes: OPTN call center operations support Meetings and logistics coordination and facilitation Financial management process improvement Health Resources and Services Administration (HRSA) SAMHSA In support of SAMHSA’s Eating Disorder Center of Excellence, we implemented: Eating disorder prevention, treatment, and awareness programs Community engagement and stigma reduction initiatives Healthcare provider training Substance Abuse and Mental Health Services Administration (SAMHSA) OS ASFR We partner with ASFR, OGA, OASH, ASA, OA, and the Immediate Office (IO) to improve operations, strengthen human capital, and modernize grants management and grants solutions across HHS. Our support includes: Department-wide financial management support Grants QSMO operations and marketplace modernization Acquisition policy development and workforce capability building Human capital planning, training, and workforce development Grants management process improvement and technology-enabled solutions Office of the Secretary (OS) Assistant Secretary for Financial Resources (ASFR) IHS We collaborate with IHS to support delivery of comprehensive health services through the Indian Health Care System for millions of American Indians and Alaska natives belonging to hundreds of federally recognized tribes across 37 states. Our support includes: Effective and efficient financial operations in support of the IHS mission, program goals, and budget plans Technical, functional, and business operations support to headquarters components and the 12 IHS Area Offices Operations and maintenance (O&M) of the IHS financial systems, implementation of new system capabilities, special projects to improve business processes, and initiatives to adapt policies, standards, and controls to comply with regulatory changes Indian Health Service (IHS) How we help Other agencies we support CDC Learn more CDC-CCC-420x280 Our work supports the CDC's mission to prevent disease and protect public health by advancing science, technology, and innovation. Centers for Disease Control & Prevention CMS CMS-420x280 Guidehouse provides a variety of technology and professional services that support CMS efforts to expand insurance coverage and improve health outcomes. Centers for Medicare & Medicaid Services FDA FDA-CCC420x280 Guidehouse brings together experts with industry and public sector experience to address challenges at the intersection of operations, policy, science, and technology. U.S. Food and Drug Administration NIH NIH-420x280 Our advisory, digital, risk management, and scientific experts support the biomedical health system and help the NIH achieve its goals. National Institutes of Health